University Of California, San Francisco,

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, United States

One of the world’s leading health sciences universities, the University of California, San Francisco (UCSF), dates its founding to 1864, when South Carolina surgeon Hugh Toland founded a private medical school in San Francisco. 

Toland had come west in 1849 to seek his fortune in the California Gold Rush, but after a few discouraging months as a miner, he set up a surgical practice in booming San Francisco. As his wealth and influence grew, he purchased land in North Beach and opened Toland Medical College.

The Affiliated Colleges, initially located at various sites in San Francisco, were united on a site overlooking Golden Gate Park — known today as Parnassus Heights. 

The college prospered, and Toland sought to affiliate with the University of California, which had opened its campus in Berkeley in 1868. UC President Daniel Coit Gilman, who strongly supported science education, set a precedent for the young university by affiliating in 1873 with both Toland Medical College and the California College of Pharmacy. Eight years later, the UC Regents added a dental college.

The three Affiliated Colleges — also called UC departments — were located at various sites in San Francisco, and after several years there was strong interest in bringing them together. San Francisco Mayor Adolph Sutro donated 13 acres on a site overlooking Golden Gate Park — known today as Parnassus Heights — and the new Affiliated Colleges buildings opened in fall 1898.